In this work, we presented microsponges enriched gel containing topical agents. The microsponge delivery system fulfills these requirements. Microsponge delivery systems are uniform, spherical polymer particles. Their high degree of cross-linking results in particles that are insoluble, inert and of sufficient strength to stand up to the high shear commonly used in manufacturing of creams, lotions, and powders. Their characteristic feature is the capacity to adsorb or load a high degree of active materials into the particle and on to its surface. Its large capacity for entrapment of actives, up to three times its weight, differentiates micro-sponge products from other types of dermatological delivery systems.