The book presents investigations into the world of info-computational nature, in which information constitutes the structure, while computational process amounts to its change. Information and computation are inextricably bound: There is no computation without informational structure, and there is no information without computational process. Those two complementary ideas are used to build a conceptual net, which according to Novalis is a theoretical way of capturing reality. We apprehend the reality within a framework known as natural computationalism, the view that the whole universe can be understood as a computational system at many different levels - from quantum mechanical world, to biological organisms including intelligent minds and their societies. Questions about nature of information and computation and their unified view are addressed along with application of info- computational approach to knowledge generation.