InhaltsangabeVolume 1:



PRINCIPLES OF TUMOR TARGETING

Limits of Conventional Cancer Chemotherapy

Pathophysiological and Vascular Characteristics of Tumors in Relation to Drug Delivery

Enhanced Permeability and Retention Effect in Relation to Tumor Targeting

Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design

Development of Cancer-Targeting Ligands and Ligand-Drug Conjugates

AntibodyDirected Enzyme Prodrug Therapy (ADEPT)
Basic Principles and its Practice So Far



TUMOR IMAGING

Imaging Techniques in Drug Development and Clinical Practice

Magnetic Nanoparticles in Magnetic Resonance Imaging and Drug Delivery

Preclinical and Clinical Tumor Imaging with SPECT/CT and PET/CT



Volume 2:



MACROMOLECULAR DRUG DELIVERY SYSTEMS

AntibodyBased Systems

Empowered Antibodies for Cancer Therapy

Mapping Accessible Vascular Targeting to Penetrate Organs and Solid Tumors

Considerations of Linker Technologies

AntibodyMaytansinoid Conjugates: From the Bench to the Clinic

Calicheamicin Antibody-Drug Conjugates and Beyond

Antibodies for the Delivery of Radionuclides

Bispecific Antibodies and Immune Therapy Targeting



POLYMERBASED SYSTEMS

Design of Polymer-Drug Conjugates

Dendritic Polymers in Oncology: Facts, Features, and Applications

SiteSpecific Prodrug Activation and the Concept of SelfImmolation

LigandAssisted Vascular Targeting of Polymer Therapeutics

Drug Conjugates with Poly(Ethylene)Glycole

ThermoResponsive Polymers

Polysaccharide-Based Drug Conjugates for Tumor Targeting

Serum Proteins as Drug Carriers of Anticancer Agents

Future Trends, Challenges, and Opportunities with Polymer-Based Combination Therapy in Cancer

Clinical Experience with Drug-Polymer Conjugates



NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS
LIPIDBASED SYSTEMS

Overview on Nanocarriers as Delivery Systems

Development of PEGylated Liposomes

Immunoliposomes

Responsive Liposomes (for Solid Tumor Therapy)

Nanoscale Delivery Systems for Combination Chemotherapy



NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS
POLYMERBASED SYSTEMS

Micellar Strcutures as Drug Delivery Systems

TailorMade Hydrogels for Tumor Delivery

pHTriggered Micelles for Tumor Delivery

AlbuminDrug Nanoparticles

Carbon Nanotubes



Volume 3:



LIGANDBASED DRUG DELIVERY SYSTEMS

CellPenetrating Peptides in Cancer Targeting

Targeting to Peptide Receptors

Aptamer Conjugates: Emerging Delivery Platforms for Targeted Cancer Therapy

Design and Synthesis of Drug Conjugates of Vitamins and Growth Factors

Drug Conjugates with Polyunsaturated Fatty Acids



SPECIAL TOPICS

RNA Drug Delivery Approaches

Local Gene Delivery for Therapy of Solid Tumors

Viral Vectors for RNA Interference Applications in Cancer Research and Therapy

Design of Targeted Protein Toxins

Drug Targeting to the Central Nervous System

Liver Tumor Targeting

Photodynamic Therapy: Photosensitizers Targeting and Delivery

TumorTargeting Strategies with Anticancer Platinum Complexes